Characterizing the Blood Stem Cell Niche (R01)

Purpose. This FOA issued by the National Heart, Lung, and Blood Institute, National Institutes of Health, solicits Research Project Grant (R01) applications in a specific area of stem cell research, the blood stem cell niche, an area critical to advancing stem cell biology and its applications to cellular therapeutics including hematopoietic stem cell transplantation. This FOA is being initiated to foster collaborative research projects and insightful approaches to dissect the cellular components and factors involved in the hematopoietic stem cell niche. Development of conditional genetic knock-out models to test the role of factors in specific cell lineages and imaging technology to facilitate following stem cell engraftment in the niche in vivo are integral to this initiative.

Key Dates
Release/Posted Date: October 17, 2008
Opening Date: December 15, 2008 (Earliest date an application may be submitted to Grants.gov)
Letters of Intent Receipt Date(s): December 8, 2008
NOTE: On-time submission requires that applications be successfully submitted to Grants.gov no later than 5:00 p.m. local time (of the applicant institution/organization).Application Due Date(s): January 6, 2009
Peer Review Date(s): April/May 2009
Council Review Date(s): May 2009
Earliest Anticipated Start Date(s): July 1, 2009
Additional Information To Be Available Date (Activation Date): Not Applicable
Expiration Date: January 7, 2009