link

August 11, Tuesday
12:00 – 13:30

Whole genome analysis of mtDNA natural evolution in human and in cancer
Computer Science seminar
Lecturer : Dr. Eitan Rubin
Lecturer homepage : http://cmsprod.bgu.ac.il/Eng/Centers/nibn/Research/ComputationalBiotechnology/EitanRubin.htm
Affiliation : Shraga Segal Department of Microbiology and Immunology, BGU
Location : 202\37
Host : Dr. Michal Ziv-Ukelson
The mitochondrial genome (mtDNA) is an exceptional model for bioinformatics. It is the only genome which was already completely sequenced in thousands of individuals. We developed a special method for comparative whole-genome analysis of mtDNA mutations in human evolution and in cancer, and show that distinct patterns recur in both. Some challenges of whole-genome analysis, especially with the ongoing “1000 genomes” data, will be demonstrated through this anlaysis.