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May 13, Tuesday
11:00 – 12:00

Flexible designs and applications of microarrays
Computer Science seminar
Lecturer : Zohar Yakhini
Lecturer homepage : http://bioinfo.cs.technion.ac.il/people/zohar/
Affiliation : Agilent Laboratories and Technion Computer Science Department
Location : 202/37
Host : Dr. Michal Ziv-Ukelson
Microarrays have evolved over recent years to address a range of genomic measurement tasks. The development of array based genome wide DNA copy number profiling has opened the door to a variety of other applications.

Manufacturing techniques that enable flexible design of probes and complete arrays in various sizes complete the picture to yield a versatile measurement platform.

I will describe the use of microarrays in several collaborative efforts, including studies of the time of replication in S phase (collaboration with HUJI), studies of chromosomal aberrations in cancer (collaborations with NCI and with Oslo University) and of copy number vaiations (CNVs) in normal populations (collaboration with Harvard). The talk will specifically address some of the computational aspects of flexible designs and applications.