The ExPASy Proteomics Server
“The ExPASy (Expert Protein Analysis System) proteomics server of the Swiss Institute of Bioinformatics (SIB) is dedicated to the analysis of protein sequences and structures as well as 2-D PAGE” and provides access to numerous databases, tools, software packages, and other information.
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Tips, Tutorials, and Terminology
Tutorials and terminology resources from the Human Genome Project
“The following tutorials are targeted to first-time users of some of the bioinformatics resources described in Genome Database Guide. Each tutorial includes step-by-step instructions and screen shots covering basic skills needed to use each Web site. Links to help files and other Web-based instructions for learning more about the different features of each bioinformatic tool are also provided.”
NCI Genomics and Bioinformatics Group Microarray Tools
The Microlarray Tools of the NCI Genomics and Bioinformatics Group:
AbMiner
MatchMiner
GoMiner
HT-GoMiner
SmudgeMiner
MedMiner
CIMminer
BITOLA – Biomedical Discovery Support System
BITOLA – Biomedical Discovery Support System
created by Dimitar Hristovski and Borut Peterlin
“BITOLA is an interactive literature-based biomedical discovery support system. The purpose of the system is to help the biomedical researchers make new discoveries by discovering potentially new relations between biomedical concepts. The set of concepts currently contains MeSH (Medical Subject Heading), which is used to index Medline, and around 22000 human genes from HUGO and LocusLink. The potentially new relations are discovered by mining the Medline database (currently around 11000000 citations from 1966 to end of 2001).
To make the system more suitable for disease candidate-gene discovery and to decrease the number of candidate relations, we integrated background knowledge about the chromosomal location of the starting disease as well as the chromosomal location of the candidate genes from resources such as LocusLink, HUGO and OMIM. The BITOLA system can also be used as an alternative way of searching the Medline database.”
NCI Creates Network of Clinical Proteomic Technology Centers for Cancer Research
An excerpt from the September 27th NCI press release:
“The National Cancer Institute (NCI), part of the National Institutes of Health, today announced funding for a major component of its $104 million, five-year Clinical Proteomic Technologies Initiative for Cancer (CPTI). Awards totaling $35.5 million over five years will establish a collaborative network of five Clinical Proteomic Technology Assessment for Cancer (CPTAC) teams. Each of these teams will bring complementary expertise to assess the full spectrum of measurement technologies for proteins and peptides relevant to clinical cancer research and practice. Proteomics is the study of the structure and function of proteins, including the way they work and interact with each other inside cells; a peptide is any compound consisting of two or more amino acids, which are the building blocks of proteins.” Read the full release here.
Databases, Toolbox, Submissions, and Downloads
EMBL-EBI European Bioinformatics Institute Databases, Toolbox, Submissions, and Downloads.
Natural Environment Research Council
“Natural Environment Research Council (NERC)
NERC supports a number of competitive grant schemes for blue skies research:
* Small Research Grants support curiosity-motivated, strategic or applied research with funding of between £2k and £30k. There is a single annual call for Small Grants with a closing date of 1 September.
* Standard Research Grants support scientifically excellent curiosity-motivated research, strategic research projects in excess of £30k funding. Closing dates 1 July, 1 December.
NERC also invites applications to its Thematic Research Programmes, which operate through calls for proposals.�
Data Mining
Tools for Data Mining from the National Center for Biotechnology Information
Environmental Genomics Data Catalogue
EnvBase: The NERC Environmental Genomics Data Catalogue from The NERC Environmental Bioinformatics Centre.
Genome Canada
�Together with its five Genome Centres and with other partners, Genome Canada invests and manages large-scale research projects in key selected areas such as agriculture, environment, fisheries, forestry, health and new technology development. Genome Canada also supports research projects aimed at studying and analyzing the ethical, environmental, economic, legal and social issues related to genomics research (GE3LS ).
To date, Genome Canada has invested more than $560 million across Canada, which, when combined with funding from other partners, is expected to result in more than $1.2 billion in 112 innovative research projects and sophisticated science and technology platforms.�