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Implicating Noncoding RNAs in the Genetics of Mental Disorders (R01) (Collaborative R01) (R21)

Implicating Noncoding RNAs in the Genetics of Mental Disorders (R01)
Implicating Noncoding RNAs in the Genetics of Mental Disorders (Collaborative R01)
Implicating Noncoding RNAs in the Genetics of Mental Disorders (R21)

Department of Health and Human Services
National Institute of Mental Health (NIMH)

Program Announcement (PA) Number: PA-07-370; PA-07-371;PA-07-372;
Opening Date: May 7, 2007 (Earliest date an application may be submitted to
Expiration Date: May 8, 2010

The purpose of this Funding Opportunity Announcement (FOA) is to invite applications that investigate the role of microRNAs and other noncoding RNAs in the etiology of mental disorders. The data generated by this effort will contribute to the disaggregation of the molecular machinery underlying mental disorders by integrating sequence specific modulators of post-transcriptional gene expression into a theoretical framework of disease pathophysiology, with the aim of rapid, widespread sharing of the resulting data to accelerate genetic analysis of human diseases.

NIH – Human Genes and the Environment Research Training Program

Human Genes and the Environment Research Training Program

Executive Summary

The National Institute of Environmental Health Sciences and the National Human Genome Research Institute will award Ruth L. Kirschstein National Research Service Award (NRSA) Institutional Research Training Grants (T32) to eligible institutions to support predoctoral, postdoctoral and short term research training to ensure the appropriate workforce is available to assume leadership roles to advance the research objectives of the Genes and Environment Initiative. This new Genes and the Environment Training Program seeks to build upon the established foundations in exposure biology and high throughput genomics to produce a new generation of scientists who are equally at home in genomics and environmental health sciences and can seamlessly interact with both groups of scientists.

The total amount to be awarded is $750,000.

The anticipated number of awards is three.

Key Dates:

Release Date: January 17, 2007
Letters of Intent Receipt Date(s): May 29, 2007
Application Receipt Date(s): June 29, 2007
Peer Review Date(s): October-November 2007
Council Review Date(s): January 2008
Earliest Anticipated Start Date: July 1, 2008
Expiration Date: June 30, 2007

Latest Fugu Assembly Available in Genome Browser

11 April 2007
Latest Fugu Assembly Available in Genome Browser

The UCSC Genome Browser now includes the latest release of the Fugu genome. The v4.0 whole genome shotgun assembly (Oct. 2004, UCSC fr2) was provided by the US DOE Joint Genome Institute (JGI) as part of the International Fugu Genome Consortium led by the JGI and the Singapore Institute of Molecular and Cell Biology (IMCB).

This version has been sequenced to approximately 8.5X coverage. The assembly contains 7,213 scaffolds covering 393,312,790 bp. The UCSC browser displays the scaffolds on the virtual chromosome chrUn with gaps of 1,000 bp between scaffolds. The scaffolds range in size from 2,223 bp to 7,245,445 bp. Fifty percent of the sequence (196,648,171 bp) is contained within 125 scaffolds of size 858,115 or greater (N50). The Fugu mitochondrial sequence is also available as the virtual chromosome chrM (GenBank accession: NC_004299.1).

Bulk downloads of the sequence and annotation data are available via the Genome Browser FTP server or Downloads page. These data have been freely provided by the JGI for use in the UCSC Genome Browser.

Many thanks to the JGI, IMCB, and the International Fugu Genome Consortium for the assembly data. The UCSC Fugu Genome Browser was produced by Cory McClean, Hiram Clawson, Ann Zweig, and Donna Karolchik. The annotation tracks were generated by UCSC and collaborators worldwide. See the Credits page for a detailed list of the organizations and individuals who contributed to this release.

IEEE 7th International Symposium on Bioinformatics & Bioengineering (BIBE 2007)

October 15-17, 2007

IEEE 7th International Symposium on Bioinformatics & Bioengineering (BIBE 2007)
Cambridge – Boston, Massachusetts, USA

Bioinformatics and Bioengineering are complementary disciplines that hold great promise for the advancement of research and development in complex medical and biological systems, agriculture, environment, public health, drug design, and so on. The BIBE Symposium provides a common platform for the cross fertilization of ideas, and to help shape knowledge and scientific achievements by bridging these two very important and complementary disciplines into an interactive and attractive forum.

– Biomedical Informatics and Computation: Bio-molecular and Phylogenetic Databases, Query Languages, Interoperability, Bio-Ontology and Data Mining, System Biology, Identification and Classification of Genes, Sequence Search and Alignment, Protein Structure Prediction and Molecular Simulation, Molecular Evolution and Phylogeny, Functional Genomics, Proteomics, Drug Discovery Gene Expression Analysis, Biolanguages, Bioinformatics Engineering, Data Visualization, Signaling and Computation Biomedical Data Engineering, Medical Image Processing (Segmentation, Registration, Fusion),Telemedicine, Modeling and Simulation, and Biomedical Imaging.

– Bio-Engineering: Biological Systems and Models, Engineering Models in Biomedicine, Image Guided Radiation Therapy, 4-D Images, Intensity Modulated Radiation Therapy, Intensity Modulated Proton Therapy, Dose Calculation and Optimization, Monte Carlo Simulation, Biological Modeling, New Technologies in MRI, PET, CAT, Mammography and Cancer Detection. Biomedical Sensors, Computer Assisted Intervention Systems and Robotics, Bionic Human, Cell Engineering, Molecular and Cellular Systems, Body’s and Cell’s Bio-signatures, Tissue Engineering, and Biomaterials.

Genomes, Medicine, and the Environment 2007

Paradise Point Resort & Spa, San Diego, California
October 8–10, 2007

The J. Craig Venter Institute this year welcomes you to sunny San Diego, California for the Genomes, Medicine and the Environment 2007 Conference. This three-day intensive meeting features presentations by world renowned genomics researchers. Meet experts in a variety of genomics disciplines, participate in interactive, in-depth discussions on future innovations in the field and network with colleagues and life sciences suppliers.


November 1 – 5, 2007

The seventh Cold Spring Harbor Laboratory/Wellcome Trust conference on Genome Informatics will be held at Cold Spring Harbor, New York. The meeting will begin on the evening of Thursday, November 1, and finish after lunch on Monday, November 5, 2007.

The focus for this conference is large-scale genome informatics. Biology is an experimental science that is experiencing an explosion of new data. This requires biologists to increase the scale and sophistication in the information technology used for their research. The conference scope encompasses the management and the analysis of these data, such as whole genome comparisons within and among species and strains, the analysis of results from high throughput experiments to uncover cellular pathways and molecular interactions, and the design of effective algorithms to identify regulatory sequence motifs.

• Epigenomics & Genetic Regulation
• Comparative & Evolutionary Genomics
• Populations, Phenotypes & Disease
• Pathways, Networks and Systems
• Images, Atlases & Reconstruction
• High Throughput Genomics

Introduction to Microarray Technology

The PFGRC announces that it will conduct a four day course titled, “Introduction to Microarray Technology�, April 16-19, 2007.

The NIAID sponsored Pathogen Functional Genomics Resource Center at TIGR announces that it will conduct a four day course titled, “ Introduction to Microarray Technology .� The workshop will be held on the TIGR campus on April 16-19, 2007. The course will provide an overview of the two-dye spotted microarray platform. The course is designed for hands on participation and attendees will actively learn to make the most of their microarrays through a combination of wet lab and bioinformatics sessions.

The wet lab portion will be taught by PFGRC staff who are directly involved in microarray production. Participants will be guided through probe preparati on and hybridizati on protocols. The training will also c on sist of detailed discussi on s on dye coupling, slide pre-hybridization, hybridization, and scanning techniques. Other topics for discussion will include the importance of assessing source material and probe quality, comparisons of various slide surfaces, and printing techniques.

The bioinformatics portion of the course covers an introduction to the stages of microarray data analysis. Major topics include data management, image analysis, normalization, and data mining. Fundamental data analysis concepts will be taught using a mix of lectures and interactive hands-on sessions. Participants will analyze the microarrays they prepared, using the open-source TM4 software suite while working closely with the software developers. CDs containing microarray datasets and the TM4 suite will be provided.

The course will be provided free of charge. Attendees will be responsible for their travel and lodging. This introductory course is one of several offered by the PFGRC on variety of functional genomics topics. Attendance will be limited to 14 participants.

Interested participants should click here for the preliminary course agenda, and here for registration information.

The SOL Genomics Network

sol genomics network
“The SOL Genomics Network (SGN) is a website dedicated to the biology of the Solanaceae family which includes a large number of closely related and many agronomically important species such as tomato, potato, tobacco, eggplant, pepper, and the ornamental Petunia hybrida.
SGN is part of the International Solanaceae Initiative (SOL), which has the long-term goal of creating a network of resources and information to address key questions in plant adaptation and diversification.�

Archon X Prize For Genomics

An October 4th posting on the Methuselah Foundation Blog announced a $10 million genomics research prize for DNA sequencing:
“We at the Methuselah Foundation are pleased to note the launch of the X Prize Foundation’s latest initiative: a $10 million genomics research prize aimed at speeding the advance of DNA sequencing. Like the cost of processing power for the computing industry, the cost of DNA sequencing is a marker for broad progress in the biotechnology revolution: the cheaper it becomes, the more can be done to advance medicine, health and longevity.”