All posts by Editor

Mouse Genetics & Genomics: Development & Disease

Mouse Genetics & Genomics: Development & Disease

October 29 – November 2, 2008
Cold Spring Harbor Laboratory (CSHL)

One Bungtown Road
Cold Spring Harbor, NY 11724
516-367-8800

You are cordially invited to participate in the twenty-first annual meeting on Mouse Genetics & Genomics: Development & Disease, which will be held at Cold Spring Harbor Laboratory. The meeting will begin with dinner and the first session on the evening of Wednesday, October 29, 2008, and will conclude with lunch on Sunday, November 2. The specific goal of this conference is to bring together a diverse group of scientists studying various molecular and genetic aspects of mammalian development. This meeting is intended to provide a format for the exchange of ideas and information, to discuss the latest research findings and technical advances towards the study of mammalian development and disease.

Pharmacogenomics NOW

Pharmacogenomics NOW
Minimize Risk & Maximize Economic Benefits

November 5-6, 2008
Omni Hotel
Montreal, Quebec

Sponsored by Cambridge Healthtech Institute

Pharmacogenomics is being implemented now and is already have an impact in the clinical setting and in healthcare. Employing a pharmacogenomics strategy with marketed drugs can mitigate risk by avoiding adverse events, allowing the identification of patients most likely to benefit from a drug, and thereby improving patient compliance and safety. Tangible benefits of pharmacogenomics and resequencing technologies will be presented, and the value of this approach will be demonstrated. The regulatory perspective will be covered from the US, Europe, and Canada. In the future, a confluence of diagnostic testing, drugs and information will be required to bring new medicines to market. This meeting will show how to apply pharmacogenomics to practice.

Analysis of gene expression in a developmental context emphasizes distinct biological leitmotifs in human cancers

Analysis of gene expression in a developmental context emphasizes distinct biological leitmotifs in human cancers

Genome Biology
8 July 2008

Background
In recent years, the molecular underpinnings of the long observed resemblance between neoplastic and immature tissue have begun to emerge. Genome-wide transcriptional profiling has revealed similar gene expression signatures in several tumor types and early developmental stages of their tissue of origin. However, it remains unclear whether such a relationship is a universal feature of malignancy, whether heterogeneities exist in the developmental component of different tumor types and to which degree the resemblance between cancer and development is a tissue-specific phenomenon.

Functional Characterization of Genetic Variants and Interactions: The Genes, Environment and Health Initiative (R21)

Functional Characterization of Genetic Variants and Interactions: The Genes, Environment and Health Initiative (R21)

The National Institute on Drug Abuse on behalf of the NIH Genes, Environment and Health Initiative encourages functional characterization of genetic variants that have been statistically nominated to be associated with a particular outcome through common, complex disease gene discovery approaches, such as genome-wide association studies, candidate gene approaches, or sequencing studies. This FOA supports research relating genetic variation to biological mechanism, or disease causality. Areas of interest include, but are not limited to, relatively low throughput approaches (e.g. transgenic mouse approaches) to test some of the most promising variants for changes in function; or exploit high-throughput tests (e.g. yeast, C. elegans, cell culture systems, or computational approaches) to look at different aspects of variant function.

Key Dates:
Release/Posted Date: April 24, 2008
Opening Date: September 17, 2008 (Earliest date an application may be submitted to Grants.gov)
Letters of Intent Receipt Date(s): September 17, 2008
NOTE: On-time submission requires that applications be successfully submitted to Grants.gov no later than 5:00 p.m. local time (of the applicant institution/organization).
Application Due Date(s): October 17, 2008
Peer Review Date(s): January/February 2009
Council Review Date(s): May 2009
Earliest Anticipated Start Date(s): July 2009
Additional Information To Be Available Date (Activation Date): Not Applicable
Expiration Date: October 18, 2008

Next-Generation Sequencing Data Analysis

Next-Generation Sequencing Data Analysis
Deciphering the Sequencing Data Deluge

September 23-25, 2008
Rhode Island Convention Center
Providence, Rhode Island

As new sequencing platforms are capable of generating gigabytes of data in a single sequence run – leading to terabytes of data in an experiment; data storage, transfer, and analysis will unquestionably be the rate limiting steps in turning the new sequence data into knowledge. CHI’s Inaugural Next-Generation Sequencing Data Analysis convenes engineers who are developing the sequencing platforms, biological researchers who are designing and running the experiments, biosatiations who are analyzing and interpreting the data, and software developers who are managing and storing the data. Each specialty provides perspectives and must be integrated into a cohesive, comprehensive team to decipher the sequencing data deluge.

58th Annual Meeting of The American Society of Human Genetics

58th Annual Meeting of The American Society of Human Genetics

Tuesday, November 11, through Saturday, November 15, 2008
Pennsylvania Convention Center
Philadelphia, Pennsylvania

The Program Committee has developed an exceptional and exciting program that will provide the highest quality scientific and clinical information to address the needs of our diverse audience. The Committee has worked to balance basic, translational, and clinical research with educational and social issues.

Molecular Genetics of Aging

Molecular Genetics of Aging

September 24 – 28, 2008
Cold Spring Harbor Laboratory
Cold Spring Harbor, NY

You are invited to participate in the fourth meeting on the Molecular Genetics of Aging, to be held at Cold Spring Harbor Laboratory, beginning after dinner at 7:30 p.m. on Wednesday, September 24, and concluding with lunch on Sunday, September 28, 2008. The meeting will explore the regulation and function of genes and processes that are now known or suspected to control cellular and/or organismic aging.

MULTIPLEXED GENOMICS TOOLS: TARGETING THE MISSING LINKS BETWEEN HEALTH AND DISEASE

MULTIPLEXED GENOMICS TOOLS:
TARGETING THE MISSING LINKS BETWEEN HEALTH AND DISEASE

September 22-23, 2008
Rhode Island Convention Center • Providence, RI

Completing the sequence of human and other genomes will soon elucidate the precise location and base sequence of every gene in a reference genome. This reference allows for rapid characterization of polymorphisms across populations. It also enables molecular fingerprinting technologies to permit identification of the precursors and consequences of normal and pathological changes in gene expression. The challenge facing current biological research is effective matching of the tool to the target. Learn from seasoned and savvy researchers who share their experience and of challenges piecing together the biological puzzle of health and disease at Cambridge Healthtech Institute’s 4th Annual Genomic Tools: Targeting the Missing Links between Health and Disease.

Functional Characterization of Genetic Variants and Interactions: The Genes, Environment and Health Initiative (R21)

Department of Health and Human Services

Functional Characterization of Genetic Variants and Interactions: The Genes, Environment and Health Initiative (R21)

Key Dates
Release/Posted Date: April 24, 2008
Opening Date: September 17, 2008 (Earliest date an application may be submitted to Grants.gov)
Letters of Intent Receipt Date(s): September 17, 2008
NOTE: On-time submission requires that applications be successfully submitted to Grants.gov no later than 5:00 p.m. local time (of the applicant institution/organization).

Application Due Date(s): October 17, 2008
Peer Review Date(s): January/February 2009
Council Review Date(s): May 2009
Earliest Anticipated Start Date(s): July 2009

Purpose. The National Institute on Drug Abuse on behalf of the NIH Genes, Environment and Health Initiative encourages functional characterization of genetic variants that have been statistically nominated to be associated with a particular outcome through common, complex disease gene discovery approaches, such as genome-wide association studies, candidate gene approaches, or sequencing studies. This FOA supports research relating genetic variation to biological mechanism, or disease causality. Areas of interest include, but are not limited to, relatively low throughput approaches (e.g. transgenic mouse approaches) to test some of the most promising variants for changes in function; or exploit high-throughput tests (e.g. yeast, C. elegans, cell culture systems, or computational approaches) to look at different aspects of variant function.


Molecular Genetics of Bacteria & Phages

Molecular Genetics of Bacteria & Phages
Fifty-ninth Meeting

August 20 – 24, 2008
Cold Spring Harbor Laboratory
Cold Spring Harbor, NY

The specific goal of this meeting is to bring together a group of scientists studying diverse aspects of prokaryotic biology using the tools of molecular biology, genetics, biochemistry, and structure analysis. The meeting is intended to provide a forum for the exchange of ideas and information and to discuss the latest research findings and technical advances. We encourage the submission of abstracts covering diverse topics and under-repesented organisms and particularly encourage junior investigators to present their results at the meeting.